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The accounting side is probably where things become a little complicated. From what I have seen, cryptocurrency is generally treated as property for tax purposes, rather like shares. This means the value is usually recorded when the donation is received, rather than when it is eventually converted to cash.
Platforms such as The Giving Block and BitPay can help with conversion and reduce some of the volatility and security concerns. There can still be setup and transaction costs, so I would check the pricing carefully before choosing one.
As for the future, I think cryptocurrency will remain a useful niche option. It may not be necessary for every nonprofit, but it could be worth considering if your supporters are comfortable with digital assets.